The Buckeyes (7-0) hit more than 64 percent of their shots from the floor, including 10-of-17 from behind the arc. Lighty's effort led four Buckeyes scored in double figures, with Evan Turner adding 17.
The Dolphins (2-6) fell despite hitting 49 percent from the floor, out rebounding the Buckeyes and creating more turnovers. Lehmon Colbert led JU in scoring and rebounds with 14 points and seven boards, as four Dolphins finished the game in double figures.
"I liked our effort tonight, but once again, it was the little things that cost us tonight," said JU head coach Cliff Warren. "You have to give credit to Ohio State. They hit the open shots when they had them and we didn't take advantage of the opportunities that we had when they turned the ball over."
Ohio State's biggest advantage came at the free throw line, as the Buckeyes shot 27 free throws in a foul-plagued contest as both teams were whistled for 43 fouls (JU 25, OSU 18). The Buckeyes hit 17 of those attempts, with the Dolphins going 9-of- 15 from the stripe.
Ohio State extended an 11-point lead to 19 early in the second half, but the Dolphins continued their tradition of second half runs - cutting the deficit to five with five to go.
The Buckeyes squashed JU's upset bid with a 10-2 run over the next four minutes to seal the victory.
Evan Jefferson tied his career high with four 3-pointers en route to 12 points, with three of those treys coming during the run to get the Dolphins back into the game.
Marcus Allen and Ben Smith each had 11 points and four assists for JU.
The Buckeyes opened the game with a hot-shooting first half, knocking down 17-of-23 from the floor, including 6-of-10 from behind the arc to take a 45-34 lead into the locker room at halftime.
Jon Diebler had 14 points and Jeremie Simmons had 10 points for the Buckeyes.